Steven Bartlett with Louisa Nicola
Alzheimer’s is not an inevitable genetic fate but a disease of lifestyle that begins decades before symptoms appear. Neurophysiologist Louisa Nicola reveals how specific exercise protocols and sleep hygiene can slash your risk by up to 95%.
Genetics (like APOE4) load the gun, but lifestyle pulls the trigger; 95% of cases are driven by preventable factors like sleep, diet, and inactivity.
Contracting muscles through heavy lifting releases "myokines" that cross the blood-brain barrier to grow new brain cells and lower inflammation.
Deep sleep activates the "glymphatic system," which physically washes away toxic amyloid-beta plaques; chronic sleep loss is a direct driver of dementia.