
Steven Bartlett with Dr Thomas Seyfried
Cancer is presented not primarily as a genetic disease, but as a metabolic disorder driven by defective mitochondria and fueled by sugar and glutamine.
Cancer cells are described as relying heavily on fermentation of glucose and the amino acid glutamine to sustain their unregulated growth.
Genetic mutations found in tumors are presented as downstream effects of mitochondrial damage rather than the root cause of the disease.
Metabolic therapy uses calorie restriction and a ketogenic diet to shift the body toward burning fatty acids and ketones, which the book argues cancer cells struggle to use effectively.